Consultation hotline 3. Question: Which lung cancer patients are suitable for treatment with Indian Iressa? Answer: Iressa is mainly used to treat locally advanced or metastatic non-small cell lung cancer that has previously received chemotherapy. , Q: Under what conditions is Indian Iressa effective in treating lung cancer? Answer: Current clinical research results show that Iressa is more effective in patients of Oriental race (mainly Asians), women, non-smokers, and patients with alveolar cell carcinoma or adenocarcinoma. Taking it on time or not will also affect the therapeutic effect. Question: India's Iressa has high efficacy against adenocarcinoma. Is it effective for patients with lung squamous cell carcinoma or other non-small cell lung cancer? Answer: The efficacy of Iressa on lung squamous cell carcinoma is lower than that on adenocarcinoma and alveolar carcinoma. However, after choosing Iressa treatment according to the patient's actual situation, some patients with lung squamous cell carcinoma and other non-small cell lung cancer can still observe significant curative effects after taking Iressa. , Q: Under what circumstances should I choose Indian Iressa treatment, and under what circumstances should I choose chemotherapy? Answer: This is a question that often confuses patients. The current research results show that there is no significant difference in the effectiveness of simultaneous use of the two and monotherapy, so simultaneous use is not recommended. Iressa is currently approved as a second-line treatment for lung cancer. It is mainly used for advanced lung cancer after chemotherapy failure. It can also be used as a first-line drug for some patients who firmly refuse to accept chemotherapy or have contraindications to chemotherapy. However, the general recommendation is to consider chemotherapy first and then Iressa treatment. After Iressa treatment fails, systemic chemotherapy may still be considered if the patient has not received chemotherapy before and his physical condition permits. In clinical practice, some patients who are determined not to undergo chemotherapy can achieve partial remission or complete regression (complete remission) of tumors after taking Iressa. However, drug resistance and tumor progression may occur after Iressa treatment for several months. At this time, significant curative effects can still be achieved after mobilizing the patient again for systemic chemotherapy. , Q: When does Indian Iressa take effect and when should it be stopped? Answer: Generally, it starts to take effect after taking it for about a week. Therefore, the efficacy can be initially evaluated after taking it for a month. The most direct way is to observe the changes of the tumor through re-examination. If the tumor does not continue to grow significantly compared with before taking the medicine, it means that it has already exerted its effect. If the drug is effective, continue to take it for a long time until tumor progression occurs again (i.e. drug resistance appears) before discontinuing or adjusting the drug. , How to determine whether Indian Iressa is effective? Answer: Whether it is effective mainly depends on two aspects. The first is the improvement of the patient's surface symptoms, such as pain relief, cough reduction, lymphatic shrinkage, mental improvement, etc. The second is the imaging examination report (), which is a comparative examination of the primary lesion and metastasis after taking it for a period of time. , if it is effective, the response on the film will be very obvious, and the tumor will no longer continue to grow significantly or gradually become smaller. It should be emphasized that the occurrence and severity of side effects such as rash, itching, and diarrhea are not the criteria for the effectiveness of Iressa, but are only for reference. Because the occurrence of side effects varies from person to person and is not absolute. , Q: Can the dosage of Indian Iressa be reduced after the economic difficulties after effective treatment? Answer: You should be very cautious when reducing or stopping the treatment after it is effective. Some patients who achieved complete tumor regression after Iressa treatment had their tumors relapse after stopping the treatment due to financial reasons or other reasons, so they needed to restart Iressa treatment. However, there are also cases where it was ineffective after stopping and then restarting the treatment. Question: What are the side effects of Iressa? Can it be taken at home? Answer: The most common side effects of Iressa are diarrhea and rash. Others include impaired liver function, nausea, vomiting, etc., but most of them are mild and can be relieved after symptomatic treatment. Side effects usually only appear in the early stages of taking the medication, and will gradually subside as the medication is continued for longer. In addition, interstitial pneumonia may occur in a very small number of patients taking Iressa, requiring immediate hospitalization. It is recommended that the patient be hospitalized in the oncology department for observation during the initial period of taking the medicine. After the condition stabilizes, the patient can return home to take the medicine, but he should still go to the hospital for regular follow-up. . Is it normal for patients to have no side effects after taking Indian Iressa? Is it a fake drug if there are no side effects? Answer: It is normal for no side effects after taking Iressa, and it does not mean that it must be a fake drug. The patient's reaction and absorption effect of the drug vary from person to person. In addition to the symptoms, it is closely related to the patient's condition, physical function conditions, timing of taking the drug and other factors. Therefore, whether there are side effects and diarrhea, etc. The degree of side effects such as rash is not certain. Some patients have obvious side effects and even cause interstitial pneumonia after taking the medicine, while some patients have not obvious side effects after taking the medicine, which is normal. Friendly reminder: Some patients are now misled into thinking that Iressa, which has no side effects after taking it, is a fake drug. This view is one-sided. Counterfeit Iressa with extremely low active ingredient content will definitely not have obvious side effects after taking it, but It cannot be said that Iressa without side effects must be fake. , Q: Is interstitial pneumonia caused by Iressa scary? Answer: The global average incidence of interstitial pneumonia caused by Iressa is about 1,000. The incidence in China is even lower, only. Fatal cases occasionally occur in Japan, but have not been reported in my country so far. We advocate that Iressa should be used with caution in individual patients with pulmonary fibrosis, extensive radiotherapy, and severely impaired lung function to prevent the occurrence of fatal interstitial pneumonia. However, a considerable number of patients with advanced lung cancer have other lung diseases (tuberculosis, emphysema, bronchial asthma, etc.), and the lungs are prone to infection. Therefore, it cannot be completely determined that all interstitial pneumonia is caused by Iressa. . , Q: How to take Iressa and when to choose? Answer: Both Iressa and Tarceva are taken orally in recommended dosages of tablets, once a day, on an empty stomach or semi-fasting. Taking into account the maximum effect of the drug and the stimulation of the gastrointestinal tract by the drug, we summarize The experience is as follows: If the patient has a good gastrointestinal tract, it is recommended to take it on an empty stomach or semi-fasting, which will be beneficial to the absorption of the drug. It is recommended to take it on an empty stomach about half an hour before breakfast every morning. If you take it on an empty stomach, you can generally choose the time between two meals. If the patient's gastrointestinal tract is not good, it is recommended to take it half an hour to an hour after a meal. It is best not to eat strong alkaline foods before and after taking the medicine, and it is not recommended to drink strong tea, but generally the impact will not be great, and you can Don't worry too much. There is no need to adjust the dosage of Iressa (gefitinib tablets) due to the following conditions: age, weight, gender, race, renal function, moderate to severe liver function damage caused by liver metastasis. Dose adjustment: When patients experience intolerable adverse reactions, they can be resolved by temporarily suspending treatment, and then the dose of one tablet per day should be resumed. If patients have difficulty swallowing, the tablets can be dispersed in half a glass of drinking water (non-carbonated drinks), but no other liquids should be used. Throw the tablets into the water without crushing, stir until completely dispersed (it will take about a minute), and drink the liquid immediately. Rinse the cup with half a cup of water and drink. The solution can also be administered via a nasogastric tube. Iressa can be taken with other Chinese and Western medicines, but in order to eliminate interactions with other drugs, please make a medication schedule and stagger the taking times of Iressa (gefitinib tablets) and other drugs to ensure that Iressa Independent medication time. ,Q: Can Iressa be taken together with traditional Chinese medicine? Answer: Both Iressa and Tarceva can be taken together with traditional Chinese medicine. The combination of traditional Chinese medicine and western medicine is also a commonly used treatment plan for patients at present. In clinical practice, when taking Iressa and Tarceva, you can also take some Chinese medicines with symptomatic and anti-cancer effects for auxiliary treatment. The specific Chinese medicine prescriptions cannot be generalized. They need to be prescribed by professional Chinese medicine doctors based on the specific conditions of the patient after on-site diagnosis. It is best to obtain the consent of the attending doctor before taking medicine. . How much is the price of Indian Iressa in China? Answer: The retail price of Iressa in Indian pharmacies was originally rupees, and was later adjusted to rupees (printed on the side of the drug packaging box), which is equivalent to about 10 yuan in RMB. Only pharmacies that purchase the whole box will give a certain discount, but they will eventually be brought home. The actual cost of Iressa plus transportation costs and necessary labor expenses is close to the Indian retail price. The quotations in the domestic market vary widely, among which the domestic retail price of RMB/box, which accounts for a relatively high proportion, is the most real and reasonable, and the profit at this price mainly depends on volume. Therefore, any Iressa currently sold on the market that is lower than the Indian retail price is generally unreliable. At present, fake Iressa manufactured by domestic counterfeiters has appeared on the Chinese market, and fake Iressa mainly attracts patients at low prices, so please be careful when purchasing, do not be too greedy for cheap, and be careful to buy fake medicines! , Iressa and Tarceva are both targeted drugs for the treatment of non-small cell lung cancer. What is the difference between the two? How should it be used clinically? Answer: Iressa and Tarceva are currently the most widely used molecularly targeted drugs for non-small cell lung cancer with the most clinically proven efficacy. The physiology and pharmacological effects of the two medicines are basically the same. They are both small molecule compounds and their curative effects are basically similar. Therefore, some doctors vividly call them sister medicines. But strictly speaking there is a difference between the two. In terms of price, the price of Tarceva is much higher than that of Iressa. The domestic retail price of Iressa in India is RMB/box, while the domestic retail price of Tarceva in India is RMB/box. In terms of efficacy, Generally speaking, the efficacy of Tarceva is stronger than that of Iressa, and the probability of corresponding side effects is also higher. In clinical practice, it is usually recommended that patients take Iressa first, and then switch to Tarceva after the patient develops resistance to Iressa, which is conducive to the continuation and in-depth treatment. In clinical practice, people who are resistant to Iressa and then take Tarceva can generally see a more obvious effect, but it is not absolute and varies from person to person. There are also some patients who fail to see obvious effects or have a longer effective period. In terms of specifications, the Indian version of Iressa and Tarceva are both 3 tablets/box. Patients take one tablet per day, and one box is a monthly dose. The difference is that Iressa is 3 tablets, while Tarceva is 3 tablets per box. In terms of properties, the surface of the Indian version of Iressa tablets is reddish brown, and the two sides of the tablets are printed with and dents respectively. The surface of Tarceva tablets is white without any words (this is a question that many patients have asked me about). , Since India's Iressa is a generic drug, isn't it a fake drug? Answer: Many people will associate it with counterfeiting when they hear the word imitation. This is one-sided. Indian Iressa is indeed a copy of British Iressa. From the perspective of intellectual property rights, the Indian version of Iressa is also It does not have international legal protection, but it is of excellent quality in terms of actual pharmaceutical ingredients and efficacy. As a country that has been a British colony for many years, India's second-largest domestic pharmaceutical group company's generic version of Iressa is almost identical to the British company AstraZeneca in terms of ingredients and production process, and the production process requires very little attention to excipients, time, temperature, and pH. It is the same as the control of bioavailability. Just because it can be dissolved in boiling water and then taken, it can reflect its stable preparation ingredients. Clinical application shows that the efficacy of Indian Iressa is basically the same as that of British Iressa. Taking Indian Iressa can also effectively control the growth and spread of cancer cells. For patients with good absorption effect, it can shrink tumors and achieve long-term control. purpose of the condition. It can be seen that the Indian version of Iressa is not strictly a fake drug, and its quality is very reliable. Consultation 3 Chen Lei WeChat account
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